Functional Genomics

Genomic Links to High Blood Lipid Levels Fine-Tuned

Bethesda, MD (Scicasts) – Combing regions of the genomes more than 17,000 people from around the world, an international team of researchers has uncovered new evidence of potential genetic influences on blood lipid levels in three ethnic groups: African Americans, East Asians and Europeans.

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Possible Link Between Tumour Suppressors and Starvation Survival

Boulder, CO (Scicasts) – A particular tumour suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing them to fend off stress, says a University of Colorado Boulder study.

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Studies Generate ‘Comprehensive’ List of Genes Required to Defend Sex Cells from Transposons

Cold Spring Harbor, NY (Scicasts) – Two teams of investigators led by Professor Gregory Hannon of Cold Spring Harbor Laboratory (CSHL) have publish studies revealing many previously unknown components of an innate system that defends sex cells – the carriers of inheritance across generations – from the ravages of transposable genetic elements.

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Key Cellular Organelle Involved in Gene Silencing Identified

Riverside, CA (Scicasts) – RNA molecules, made from DNA, are best known for their role in protein production. MicroRNAs (miRNAs), however, are short (~22) nucleotide RNA sequences found in plants and animals that do not encode proteins but act in gene regulation and, in the process, impact almost all biological processes ― from development to physiology to stress response.

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Study Finds Couch Potatoes May Be Genetically Predisposed to Being Lazy

Columbia, MO (Scicasts) – Studies show 97 percent of American adults get less than 30 minutes of exercise a day, which is the minimum recommended amount based on federal guidelines. New research from the University of Missouri suggests certain genetic traits may predispose people to being more or less motivated to exercise and remain active.

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