Sector's Activity Matrix

3 Months Ending Apr/23/2014
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Basic Research Fuels Medical Advances

Bethesda, MD (Scicasts) — This image may look complicated, but it tells a fairly straightforward tale about basic research: Learning more about basic life processes can pave the way for medical and other advances.

1.07k Engagements 5 Shares

Amino Acid Fingerprints Revealed in New Study

Tempe, AZ (Scicasts) – Some three billion base pairs make up the human genome – the floorplan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights relevant to human health and disease.

2.37k Engagements 15 Shares

New Epidemiology Model Combines Multiple Genomic Data

Providence, RI (Scicasts) – The difference between merely throwing around buzzwords like "personalized medicine" and "big data" and delivering on their medical promise is in the details of developing methods for analyzing and interpreting genomic data.

2.69k Engagements 11 Shares

Congenital Heart Disease Gene Found

Hinxton, UK (Scicasts) – Researchers have explored the role of a master gene that controls the functioning of other genes involved in heart development. Variations in this gene - NR2F2 - are responsible for the development of severe forms of congenital heart disease.

2.49k Engagements 34 Shares

New Technique for Identifying Gene-Enhancers

Berkeley, CA (Scicasts) – An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers - sequences of DNA that act to amplify the expression of a specific gene – in the genomes of humans and other mammals.

3.22k Engagements 13 Shares

APC and Colon Cancer: Location Matters

Kansas City, KS (Scicasts) – Proteins, like people, can be complex and mysterious – at least to the scientists studying them. Some two decades after discovering adenomatous polyposis coli (APC), researchers are still puzzling out this particular protein’s secrets.

3.25k Engagements 13 Shares

Bacterial Reporters That Get the Scoop

Cambridge, MA (Scicasts) – It's a jungle in there. In the tightly woven ecosystem of the human gut, trillions of bacteria compete with each other on a daily basis while they sense and react to signals from the immune system, ingested food, and other bacteria.

4.64k Engagements 7 Shares

Big Data Tackles Tiny Molecular Machines

Houston, TX (Scicasts) – Open, feed, cut. Such is the humdrum life of a motor molecule, the subject of new research at Rice University, that eats and excretes damaged proteins and turns them into harmless peptides for disposal.

4.18k Engagements 12 Shares

Finding the Switch: Researchers Create Roadmap for Gene Expression

Raleigh, NC (Scicasts) – In a new study, researchers from North Carolina State University, UNC-Chapel Hill and other institutions have taken the first steps toward creating a roadmap that may help scientists narrow down the genetic cause of numerous diseases.

1.56k Engagements 6 Shares

Study Shows Leukaemia Caused by Chromosome Catastrophe

Hinxton, UK (Scicasts) – Researchers have found that people born with a rare abnormality of their chromosomes have a 2,700-fold increased risk of a rare childhood leukaemia. In this abnormality, two specific chromosomes are fused together but become prone to catastrophic shattering.

3.52k Engagements 10 Shares

Taking Immune Cells for a Test Drive

Cambridge, MA (Scicasts) – You’re on a crowded subway car and someone nearby sneezes. Influenza viruses shed by your fellow rider are expelled in droplets of saliva that land on you and the person next to you. Two days later, you begin suffering from the classic flu symptoms of fever, aches, and runny nose, while the lucky rider next to you somehow dodges the infectious bullet.

2.54k Engagements 7 Shares

Cancer Therapy May Be Too Targeted

Hinxton, UK (Scicasts) – Researchers have identified two novel cancer genes that are associated with the development of a rare, highly aggressive, cancer of blood vessels. These genes may now act as markers for future treatments and explain why narrowly targeted therapies that are directed at just one target fail.

2.94k Engagements 9 Shares

A Novel Mechanism for Fast Regulation of Gene Expression

St. Louis, MO (Scicasts) – Our genome, we are taught, operates by sending instructions for the manufacture of proteins from DNA in the nucleus of the cell to the protein-synthesizing machinery in the cytoplasm. These instructions are conveyed by a type of molecule called messenger RNA (mRNA). [Videos]

4.17k Engagements 10 Shares

Newly Identified Small-RNA Pathway Defends Genome Against the Enemy Within

Cold Spring Harbor, NY (Scicasts) – Reproductive cells, such as an egg and sperm, join to form stem cells that can mature into any tissue type. But how do reproductive cells arise? We humans are born with all of the reproductive cells that we will ever produce. But in plants things are very different.

4.08k Engagements 5 Shares