Scicasts

Genomics

  Sector's Activity Matrix

3 Months Ending Jul/29/2014
Latest Developments

Genetic Cause of Common Breast Tumours in Women Discovered

Singapore (Scicasts) —  A multi-disciplinary team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Singapore General Hospital have made a seminal breakthrough in understanding the molecular basis of fibroadenoma, one of the most common breast tumours diagnosed in women.

1.08k Engagements 9 Shares

Speedy Computation Enables Scientists to Reconstruct an Animal’s Development Cell by Cell

Chevy Chase, MD (Scicasts) — Recent advances in imaging technology are transforming how scientists see the cellular universe, showing the form and movement of once grainy and blurred structures in stunning detail. But extracting the torrent of information contained in those images often surpasses the limits of existing computational and data analysis techniques, leaving scientists less than satisfied.

1.52k Engagements 10 Shares
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New Technique Maps Life's Effects on Our DNA

London, UK (Scicasts) — Researchers at the BBSRC-funded Babraham Institute, in collaboration with the Wellcome Trust Sanger Institute Single Cell Genomics Centre, have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents.

1.28k Engagements 5 Shares

Scientists Complete Chromosome-Based Draft of the Wheat Genome

Manhattan, KS (Scicasts) — Several Kansas State University researchers were essential in helping scientists assemble a draft of a genetic blueprint of bread wheat, also known as common wheat. The food plant is grown on more than 531 million acres around the world and produces nearly 700 million tons of food each year.

1.63k Engagements 6 Shares

Agreement Will Accelerate Genetic Disease Research Worldwide

Hinxton, UK (Scicasts) — Academic and industry researchers worldwide will be able to carry out research and development into human disease more rapidly due to a non-exclusive partnership between European Conditional Mouse Mutational Program (EUCOMM) members Wellcome Trust Sanger Institute and Helmholtz Zentrum München, and genOway, a specialist producer and distributer of modified mouse resources.

1.67k Engagements 8 Shares

It May Take Guts to Cure Diabetes

New York, NY (Scicasts) — By switching off a single gene, scientists at Columbia University’s Naomi Berrie Diabetes Center have converted human gastrointestinal cells into insulin-producing cells, demonstrating in principle that a drug could retrain cells inside a person’s GI tract to produce insulin.

1.57k Engagements 4 Shares
Featured

How DNA Protects Itself from UV Light

Menlo Park, CA (Scicasts) — The molecular building blocks that make up DNA absorb ultraviolet light so strongly that sunlight should deactivate them – yet it does not. Now scientists have made detailed observations of a “relaxation response” that protects these molecules, and the genetic information they encode, from UV damage.

4.65k Engagements 41 Shares

Vast Genetic Diversity Among Mexicans Found in Large-Scale Study

Stanford, CA (Scicasts) — The first large-scale, comprehensive analysis of the genomic diversity of Mexico — led by researchers at the Stanford University School of Medicine, the University of California-San Francisco and the Mexican National Institute of Genomic Medicine — has identified a dazzling mosaic of genotypes and population substructures across the country.

2.17k Engagements 2 Shares

Common Gene Variants Account for Most Genetic Risk for Autism

Bethesda, MD (Scicasts) — Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches, researchers funded by the National Institutes of Health have found. Heritability also outweighed other risk factors in this largest study of its kind to date.

1.21k Engagements 5 Shares

Neutron Crystallography Solves Long-Standing Biological Mystery

Leicester, UK (Scicasts) — An international team of researchers, led by the University of Leicester, has solved a long-standing mystery in biology, by identifying the molecular structure of a vital biological chemical. The debate – which has raged within the scientific community for years – boils down to something as simple as a hydrogen atom: is it there, or is it not?

1.58k Engagements 6 Shares

How Knots Can Swap Positions on a DNA Strand

Mainz, Germany (Scicasts) — Physicists of Johannes Gutenberg University Mainz (JGU) and the Graduate School of Excellence "Materials Science in Mainz" (MAINZ) have been able with the aid of computer simulations to confirm and explain a mechanism by which two knots on a DNA strand can interchange their positions.

1.75k Engagements 13 Shares

Mosquito Species Swap Insecticide-Resistance Genes

Hinxton, UK (Scicasts) — Researchers have exploited a natural experiment created by our use of insecticides to show that large regions of DNA can move between the two types of mosquito that are most important in spread of malaria.

1.93k Engagements 12 Shares

Researchers Explore the Genetic Underpinnings of Nerve-Cell Spacing

Santa Barbara, CA (Scicasts) — The functional organization of the central nervous system depends upon a precise architecture and connectivity of distinct types of neurons. Multiple cell types are present within any brain structure, but the rules governing their positioning, and the molecular mechanisms mediating those rules, have been relatively unexplored.

1.97k Engagements 15 Shares

A New Tool to Confront Lung Cancer

Salt Lake City, UT (Scicasts) — Only 15% of patients with squamous cell lung cancer – the second most common lung cancer – survive five years past diagnosis. Little is understood about how the deadly disease arises, preventing development of targeted therapies that could serve as a second line of defence once standard chemotherapy regimens fail.

1.54k Engagements 2 Shares

Exploring a Parasitic Tunnel Boring Machine

Hinxton, UK (Scicasts) — Researchers have deduced essential biological and genetic information from the genome sequence of the whipworm, an intestinal parasitic worm that infects hundreds of millions of people in developing countries. This information acts as the foundation for the development of new strategies and treatments against this debilitating parasite.

2.08k Engagements 4 Shares

Researchers Chart Cellular Complexity of Brain Tumours

Cambridge, MA (Scicasts) — Scientists from the Broad Institute and Massachusetts General Hospital (MGH) have conducted a first-of-its-kind study that characterizes the cellular diversity within glioblastoma tumours from patients.

2.74k Engagements 9 Shares