Bio-IT & Biotechnology
Cresset Introduces FieldStere V2.0
Hertfordshire, UK (Scicasts) - Cresset, a UK-based company developing software for calculating and comparing the molecular Field characteristics of chemical compounds, has announced the release of a new version of its FieldStere bioisostere generator. FieldStere delivers shorter lead optimization cycles to computational and medicinal chemists by enabling them to choose the best syntheses, to fine-tune portions of lead molecules and to scaffold hop to expand into new areas of chemical space.
New Compounds Discovered Open Doors for New Class of AIDS Drug
HIV Virus Simulation
La Jolla, CA (Scicasts) - A team of researchers at the Scripps Research Institute has discovered two new compounds that prove the existence of new binding sites on HIV protease. Associate Professor C. David Stout, senior author of the study, explained “These results open the door to a whole new approach to drug design against HIV protease,” which is an enzyme used by HIV to create new, infectious viral particles.
IBM Donates Supercomputer to Rice University
Houston, TX (Scicasts) - Rice University and IBM have unveiled a new high-performance computing (HPC) initiative for biomedical and life sciences research that features one of the most powerful supercomputers in the Texas Medical Center. According to the announcement, Rice scientists will use the supercomputer in collaboration with researchers from across the medical centre to study cancer, AIDS and other complex diseases.
Scientists Develop Universal DNA Reader
As a single chemical base of DNA (blue atoms) passes through a tiny, 2.5nm gap between two gold electrodes (top and bottom), it momentarily sticks to the electrodes (purple bonds) and a small increase in the current is detected. Each of the chemical bases of the DNA genetic code, abbreviated A, C, T or G, gives a unique electrical signature as they pass between the electrodes.
Phoenix, AZ (Scicasts) - According to a report from Arizona State University, scientists at the Institute have come up with a new twist in their efforts to develop a faster and cheaper way to read the DNA genetic code. They have developed a versatile DNA reader that can discriminate between DNA's four core chemical components–the key to unlocking the vital code behind human heredity and health.
NVIDIA Launches Tesla Bio Workbench
The Tesla Bio Workbench from NVIDIA
Santa Clara, CA (Scicasts) - NVIDIA has announced the launch of its Tesla Bio Workbench, which according to the company, enables scientists to push the boundaries of biological research by turning a standard PC into a “computational laboratory” capable of running complex bioscience codes in fields such as drug discovery and DNA sequencing more than 10-20 times faster through the use NVIDIA Tesla GPUs.
EMBL-EBI Launches Open Access Drug Discovery Database
Hinxton and London (Scicasts) - ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launched earlier this week with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new drugs in the clinic.
Neuroengineers Develop Tool That Could Help Treat Brain Disorders
Cambridge, MA (Scicasts) - Neuroscientists at MIT have announced the development of a powerful new class of tools that they believe could reversibly shut down brain activity using different colours of light. When targeted to specific neurons, these tools could potentially lead to new treatments for the abnormal brain activity associated with disorders such as chronic pain, epilepsy, brain injury, and Parkinson's disease.
Symyx Releases Symyx Notebook 6.4
Sunnyvale, CA (Scicasts) - Symyx Technologies has unveiled the release of Symyx Notebook 6.4., offering scientists improved support for method development, validation and execution in regulated and non-regulated analytical labs. According to the announcement, this latest release of Symyx's electronic lab notebook (ELN) offers new cross-experiment referencing and reporting capabilities that improve collaborative workflows for multidisciplinary teams working in the life sciences, chemicals, energy and consumer products industries.
Researchers Develop “Nano Cocktail” to Target and Kill Tumours
La Jolla, CA (Scicasts) - A team of researchers in California and Massachusetts has developed a “cocktail” of different nanometre-sized particles that work in concert within the bloodstream to locate, adhere to and kill cancerous tumours.
Carbon Nanotubes Show Promise for High-speed Genetic Sequencing
Mesa, AZ (Scicasts) - Faster sequencing of DNA holds enormous potential for biology and medicine, particularly for personalized diagnosis and customized treatment based on each individual's genomic makeup. At present however, sequencing technology remains cumbersome and cost prohibitive for most clinical applications, though this may be changing, thanks to a range of innovative new techniques.
CLC bio Releases Beta Version of de novo Assembler
Aarhus, Denmark (Scicasts) - CLC bio has announced the release of the beta version of their long awaited assembly algorithm for de novo assembly to selected customers and now it’s publically available. The new assembler comes in two different editions, as a standalone command-line interface and as a graphical user interface through a plug-in for CLC Genomics Workbench.
MEDINA Scientists License Genedata Screener for Lead Discovery from Natural Products
Basel, Switzerland, and Granada, Spain (Scicasts) - Genedata, a provider of advanced software solutions for drug discovery and life science research, and Fundación MEDINA (Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía), have announced their collaboration in the discovery of innovative medical compounds to fight infectious diseases, cancer and immune disorders. MEDINA has licensed the Genedata Screener platform - including the modules Condoseo for dose-response curve fitting and Kinetics Analyzer for the capture of time series data - for rapid and flexible data processing, management and analysis for all of their natural product screening and lead evaluation services. Those services span a wide range of assay technologies and instrumentation, from single-plate measurements to large-scale screens.
NAG Unveils the Release of the NAG TOOLBOX FOR MATLAB
Oxford, UK (Scicasts) - According to an announcement from the Numerical Algorithms Group (NAG), researchers, application developers and other users of technical computing software seeking a broad range of mathematical and statistical functionality without the considerable expense and bother of sourcing multiple MATLAB toolboxes, can now access 1,415 rigorously tested numerical routines in the Mark 22 Release of the multipurpose NAG TOOLBOX FOR MATLAB.
Petascale Computing Tools Could Provide Deeper Insight into Genomic Evolution
Atlanta, Georgia (Scicasts) - Technological advances in high-throughput DNA sequencing have opened up the possibility of determining how living things are related by analyzing the ways in which their genes have been rearranged on chromosomes. However, inferring such evolutionary relationships from rearrangement events is computationally intensive on even the most advanced computing systems available today.
Scientists Create Social Networking Tool
London, UK (Scicasts) - According to a report published this week in the open access journal, BMC Bioinformatics, researchers at London's Natural History Museum have created a social networking tool called 'Scratchpads' where natural historians can get together and share their data.
New Imagining Technique Could Lead to Better Antibiotics and Cancer Drugs
College Station, TX (Scicasts) - According to a report by a Texas AgriLife Research scientist, a recently devised method of imaging the chemical communication and warfare between microorganisms could lead to new antibiotics, antifungal, antiviral and anti-cancer drugs.
DNA Barcodes: New Uses Span Health, Fraud, Smuggling, History and More
Washington, DC (Scicasts) - The Consortium for the Barcode of Life (CBOL), an international initiative devoted to developing DNA barcoding as a global standard for the identification of biological species, has unveiled that DNA "barcoding" is being embraced and applied by a growing legion of global authorities – from medical and agricultural researchers to police and customs authorities to palaeontologists and others.
GenoLogics and CLC bio to Provide End-to-End Genomics Informatics and Analysis for Next Generation Sequencing
Victoria, BC, Canada and Aarhus, Denmark (Scicasts) - GenoLogics and CLC bio have unveiled that they will provide an end-to-end informatics and analysis solution, optimized for Next Generation Sequencing research that addresses both lab and data management and data analysis all within one integrated system.
Henk Stunnenberg's Lab Uses Genomatix NextGen Sequencing Data Analysis
Ann Arbor, MI (Scicasts) - Genomatix Software, a provider of solutions for the comprehensive analysis of Next Generation Sequencing (NGS) data, has announced that the Nijmegen Centre for Molecular Life Sciences (NCMLS) installed a Genomatix Genome Analyzer (GGA) at Henk Stunnenberg´s lab. Henk Stunnenberg, a pioneer in transcription factor analysis and epigenetic research, is full professor, head of the Department of Molecular Biology, and a member of EMBO.
PNNL Scientist Honoured for Pioneering Development of Proteomics Tools
Toronto, CA (Scicasts) - Laboratory and Battelle Fellow Dick Smith of the Department of Energy's Pacific Northwest National Laboratory has been recognized for his many accomplishments in pioneering the development of proteomics tools. Scientists use these instruments to study the array of proteins and related molecules that make up much of human blood and tissues.
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