La Jolla, CA (Scicasts) – Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumours in Cushing's disease, a development that may give clinicians a therapeutic target to treat this potentially life-threatening disorder.
La Jolla, CA (Scicasts) – Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases.
Ann Arbor, MI (Scicasts) – Every day, millions of people with bipolar disorder take medicines that help keep them from swinging into manic or depressed moods. But just how these drugs produce their effects is still a mystery.
Jupiter, FL (Scicasts) – Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet―incurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems.
London, UK (Scicasts) – A study from researchers at the Wellcome Trust Centre for Neuroimaging has shown that a drug widely used to treat Parkinson’s disease can help to reverse age-related impairments indecision making in some older people.
La Jolla, CA (Scicasts) – A team of scientists, including researchers from the Salk Institute for Biological Studies, has discovered that a drug used to treat canker sores appears to reverse obesity in mice.
La Jolla, CA (Scicasts) – Autism results from abnormal cell communication. Testing a new theory, researchers at the University of California, San Diego School of Medicine have used a newly discovered function of an old drug to restore cell communications in a mouse model of autism, reversing symptoms of the devastating disorder.
Los Alamos, NM (Scicasts) – A study by researchers from Los Alamos National Laboratory and a multinational team reveals how daclatasvir, a direct-acting antiviral agent in development for the treatment of hepatitis C virus (HCV), targets one of its proteins and causes the fastest viral decline ever seen with anti-HCV drugs – within 12 hours of treatment.
Los Angeles, CA (Scicasts) – In a discovery that could derail the popular "Hangover" movie franchise, a team of researchers led by UCLA engineers has identified a method for speeding up the body's reaction to the consumption of alcohol.
Houston, TX (Scicasts) – Cancer researchers from Rice University suggest that a new man-made drug that's already proven effective at killing cancer and drug-resistant bacteria could best deliver its knockout blow when used in combination with drugs made from naturally occurring toxins.
Ann Arbor, MI (Scicasts) – Researchers at the University of Michigan's Life Sciences Institute have found that amlexanox, an off-patent drug currently prescribed for the treatment of asthma and other uses, also reverses obesity, diabetes and fatty liver in mice.
La Jolla, CA (Scicasts) – Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer. [Video]
Cambridge, MA (Scicasts) Vaccines usually consist of inactivated viruses that prompt the immune system to remember the invader and launch a strong defence if it later encounters the real thing. However, this approach can be too risky with certain viruses, including HIV.
Stockholm, Sweden (Scicasts) – Scientists at Karolinska Institutet have reported a new principle for fighting bacterial infections, in other words, a new type of antibiotic.
Troy, NY (Scicasts) – Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer's disease and Parkinson's disease, as well as Type 2 diabetes, according to a new study.
Ann Arbor, MI (Scicasts) – Are you good at coping when life gets tough? Do people call you a straight-shooter? Will you help others without expecting anything in return?
Columbus, OH (Scicasts) – First developed in the 1950s, beta blockers have been a mainstay in medicine for decades, used to treat everything from heart disease to stage fright to glaucoma. But some older classes of beta blockers are causing new concerns.