Neurodegeneration

Researchers Discover Endogenous Antibiotic in the Brain

Luxembourg (Scicasts) – Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid.

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Scientists Unravel Central Mystery of Alzheimer's Disease

La Jolla, CA (Scicasts) – Scientists at The Scripps Research Institute (TSRI) have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

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Researchers Create Next-Generation Alzheimer's Disease Model

Bethesda, MD (Scicasts) – According to a report from the NIH’s National Institute of Neurological Disorders and Stroke, a new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer’s disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the disease.

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Sleep Loss Precedes Alzheimer’s Symptoms

St. Louis, MO (Scicasts) – According to a report by researchers at the Washington University School of Medicine in St. Louis, sleep is disrupted in people who likely have early Alzheimer’s disease but do not yet have the memory loss or other cognitive problems characteristic of full-blown disease.

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Study Links Excess Protein to Development of Parkinson's Disease

La Jolla, CA (Scicasts) – Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the terminal extensions of neurons and working its way back to the cells' center, with the potential consequence of progressive degeneration and eventual cell death.

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Better Way to Culture Central Nervous Cells

Providence, RI (Scicasts) ― A protein associated with neuron damage in people with Alzheimer's disease is surprisingly useful in promoting neuron growth in the lab, according to a new study by engineering researchers at Brown University.

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