La Jolla, CA (Scicasts) – Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumours.
London, Ontario, Canada (Scicasts) – Research from Western has identified new hormones in the body which may suppress breast cancer and stimulate the regression of breast tumours.
Denver, CO (Scicasts) – When turned on, the gene p53 turns off cancer. However, when existing drugs boost p53, only a few tumours die – the rest resist the challenge.
Washington, DC (Scicasts) – Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer ― source of a serious medical problem, scientists are reporting.
Singapore (Scicasts) – Scientists from Nanyang Technological University (NTU) and Lund University, Sweden, have bioengineered a novel molecule which has been proven to successfully kill tumour cells.
Columbus, OH (Scicasts) – New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells’ “superpower” to escape death.
Champaign, IL (Scicasts) – In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumour growth.
Worcester, MA (Scicasts) – Findings from two new cancer studies yield the best evidence yet that cancer may be better defined by its genetics than the organ in which it originates. These new findings will impact both research and treatment at UMass Medical School and the UMass Memorial Cancer Center of Excellence. [Video]
Philadelphia, PA (Scicasts) – In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers.
Cambridge, MA (Scicasts) – When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA.
La Jolla, CA (scicasts) – Researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center report that cancers physically alter cells in the lymphatic system – a network of vessels that transports and stores immune cells throughout the body – to promote the spread of disease, a process called metastasis.
Columbus, OH (Scicasts) – A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukaemia that has normal-looking chromosomes under the microscope (that is, cytogenetically normal acute myeloid leukaemia, or CN-AML).
Victoria, Australia (Scicasts) – The understanding of how a powerful protein called p53 protects against cancer development has been upended by a discovery by Walter and Eliza Hall Institute researchers.
Cambridge, MA (Scicasts) – Investigators from The Cancer Genome Atlas (TCGA) Research Network, including several scientists from the Broad Institute, have published the most comprehensive genomic analysis of endometrial cancer to date.
Boston, MA (Scicasts) – Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized for growth in one-cell deep sheets to form disordered clumps that eventually become tumours.
Lund, Sweden (Scicasts) – A single antibody could be the key to treating multiple myeloma, or cancer of the blood, currently without cure or long-term treatment.
Oeiras, Portugal (Scicasts) – Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis.