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NIBIB Awards Case Western Reserve University $4M Grant

NIBIB Awards Case Western Reserve University $4M Grant

Cleveland, Ohio (OBBeC) – The Case Western Reserve University School of Medicine has announced that it has has received a $4 million grant from the National Institute of Biomedical Imaging and Bioengineering, a division of the National Institutes of Health (NIH), to fund the Case Center for Synchrotron Biosciences.

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Software Tools that Improve Identification of Cancer Biomarkers Earn Certification

Software Tools that Improve Identification of Cancer Biomarkers Earn Certification

Atlanta, Georgia (OBBeC) - The explosive growth of genomic and proteomic data has ushered in a new era of molecular medicine in which cancer detection, diagnosis and treatment are tailored to each individual's molecular profile. But this personalized medicine approach requires that researchers discover and link biomarkers -- such as genes or proteins -- to specific disease behaviours, such as the rate of tumour progression and different responses to treatments.

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New Genome-analysis Strategy Passes Initial Test

New Genome-analysis Strategy Passes Initial Test

Seattle, WA (OBBeC) - According to a recent publication in Nature by the University of Washington (UW), researchers at the Institute have successfully developed a novel genome-analysis strategy for more rapid, lower cost discovery of possible gene-disease links. By saving time and lowering expenses, the approach makes it feasible for scientists to search for disease-causing genes in people with the same inherited disorder but without any family ties to each other.

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Genetic Glitches Linked to Common Childhood Cancer

Genetic Glitches Linked to Common Childhood Cancer

Gainesville, FL (OBBeC) - According to a report from the University of Florida, a multicentre team of childhood cancer researchers has discovered two genetic variations linked to an increased risk for acute lymphoblastic leukemia, or ALL, the most common childhood cancer in the United States.

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Mathematical Model Mimics Cell Division in Carbon-cycling Bacterium

Mathematical Model Mimics Cell Division in Carbon-cycling Bacterium

Blacksburg, VA (OBBeC) - Scientists from the Department of Biological Sciences and the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a quantitative, mathematical model of DNA replication and cell division for the bacterium Caulobacter crescentus. C. crescentus, an alpha-proteobacterium that inhabits freshwater, seawater and soils, is an ideal organism for genetic and computational biology studies due to the wealth of molecular information that has been accumulated by researchers. It also plays a key role in global carbon cycling in its natural environment.

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Beckman Coulter Announces Coulter Genomics

Beckman Coulter Announces Coulter Genomics

Beverly, MA (OBBeC) - Beckman Coulter has announced the creation of Beckman Coulter Genomics. The new company, which combines Agencourt Bioscience and the newly acquired Cogenics, offers researchers a single genomic services resource with expanded global capabilities.
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Patent Awarded to Metabolon for Metabolomics Software

Patent Awarded to Metabolon for Metabolomics Software

Research Triangle Park, NC (OBBeC) - Metabolon, a provider of metabolomics-driven biomarker discovery and analysis, has announced that it has been awarded a patent for its metabolomics software, Ion Tracker, which provides a mechanism for creating new chemical library entries. The software is designed to greatly accelerate and automate the organization of ion features for mass spectrometry into chemically related sets and expedites the creation of a metabolite library. It is a key component of the company’s global biochemical profiling technology.
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SGI Announces Availability of  CloudRack X2

SGI Announces Availability of CloudRack X2

Fremont, CA (OBBeC) - SGI has announced the immediate availability of CloudRack X2, a new generation of scalable workgroup clusters for HPC, graphics and Internet applications.
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Standard Graphical Notation for Biology Launched

Standard Graphical Notation for Biology Launched

Hinxton, UK (OBBeC) - Researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) and their colleagues in 30 labs worldwide have released a new set of standards for graphically representing biological information – the biology equivalent of the circuit diagram in electronics. This visual language should make it easier to exchange complex information, so that models are accurate, efficient and readily understandable. The new standard, called the Systems Biology Graphical Notation (SBGN), is published in Nature Biotechnology.
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Researchers Show How Genetic Variations Produce Different Effects, Depending on the Tissue

Researchers Show How Genetic Variations Produce Different Effects, Depending on the Tissue

A collaboration between researchers at the Wellcome Trust Sanger Institute in the United Kingdom and the Faculty of medicine of the University of Geneva has demonstrated how DNA variation that controls and regulates the gene activity acts predominantly in a tissue-specific manner. In approximately 4 out of 5 cases, genetic variations will produce different effects depending on the tissue investigated.
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Calcium Sensor Calmodulin Captured in Action

Calcium Sensor Calmodulin Captured in Action

München, Germany (OBBeC) - It's well known that the protein calmodulin specifically targets and steers the activities of hundreds of other proteins – mostly kinases – in our cells, thus playing a role in physiologically important processes ranging from gene transcription to nerve growth and muscle contraction But just how it distinguishes between target proteins is not well understood.
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Time for Some New PCs, Not Just Upgraded Ones

For over 15 years computers have played a crucial role in our world and have revolutionized our lives to such an extent that we feel we simply can no longer live without them. This statement may seem dramatic and may be argued by some, but let’s face it, we have become so dependent on computers that even for the simplest piece of information the first source we turn to is, you guessed it, the Internet, via computers.

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Small Things Getting Big Importance

Size is becoming one of the key success factors today across many industries in this shrinking world. From cars to iPods, we see size and opportunity becoming more inversely proportional. Healthcare sector is no different in this trend. When it comes to instruments used in research/ diagnostics laboratories or even in point-of-care setting, reducing the foot print is given a top priority. Advancements in the development of micro total analysis systems (uTAS or mTAS) or lab-on-chip has slowly gained importance in various fields of which lifesciences is one of the major application areas.

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Researchers Discover Key to Keeping Cells in Shape

Researchers Discover Key to Keeping Cells in Shape

New Haven, CT (OBBeC) - Yale University researchers have discovered how a protein within most cell membranes helps maintain normal cell size, a breakthrough in basic biology that has implications for a variety of diseases such as sickle cell anemia and disorders of the nervous system.
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